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Structure−Activity Relationship of a Series of Inhibitors of Monoacylglycerol HydrolysisComparison with Effects upon Fatty Acid Amide Hydrolase †

✍ Scribed by Cisneros, José Antonio; Vandevoorde, Séverine; Ortega-Gutiérrez, Silvia; Paris, Clément; Fowler, Christopher J.; López-Rodríguez, María L.


Book ID
121470481
Publisher
American Chemical Society
Year
2007
Tongue
English
Weight
289 KB
Volume
50
Category
Article
ISSN
0022-2623

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Quantitative structure–activity relation
✍ Peng Lu; Ruisheng Zhang; Yongna Yuan; Zhiguo Gong 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 345 KB 👁 2 views

## Abstract A quantitative structure activity relationship (QSAR) analysis was performed on the $K\_i $ values of a series of fatty acid amide hydrolase (FAAH) inhibitors. Six molecular descriptors selected by CODESSA software were used as inputs to perform heuristic method (HM) and support vector