Structure−Activity Relationship of 6-Methylidene Penems Bearing Tricyclic Heterocycles as Broad-Spectrum β-Lactamase Inhibitors: Crystallographic Structures Show Unexpected Binding of 1,4-Thiazepine Intermediates

✍ Scribed by Venkatesan, Aranapakam M.; Gu, Yansong; Santos, Osvaldo Dos; Abe, Takao; Agarwal, Atul; Yang, Youjun; Petersen, Peter J.; Weiss, William J.; Mansour, Tarek S.; Nukaga, Michiyoshi; Hujer, Andrea M.; Bonomo, Robert A.; Knox, James R.

• Book ID: 125495238
• Publisher: American Chemical Society
• Year: 2004
• Tongue: English
• Weight: 487 KB
• Volume: 47
• Category: Article
• ISSN: 0022-2623
• DOI: 10.1021/jm049680x