Abbreoiutions: ADP, adenosin 5'-diposphate; CDP, cytidine 5'-diphosphate; GDP, guanosine 5'-diphosphate; TDP, thymidine 5'-diphosphate. UDPG ( = UDP-Glc), uridine 5
✦ LIBER ✦
Structure Revision of the Rauwolfia Alkaloid Raucaffricine
✍ Scribed by Helmut Schübel; Arno Treiber; Joachim Stökigt
- Publisher
- John Wiley and Sons
- Year
- 1984
- Tongue
- German
- Weight
- 257 KB
- Volume
- 67
- Category
- Article
- ISSN
- 0018-019X
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
The previous structure of the Rauwolfia alkaloid raucaffricine (vomilenine‐α‐D‐galactoside) has been revised to be vomilenine‐β‐D‐Glucoside by enzymatic and NMR studies.
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## Abstract The total synthesis of the two isomeric macrocyclic enamides **2** and **17** is described. The precursor **14** was synthesized by means of template‐assisted macrocyclization (__Scheme 2__). Isomerization of **14** in the presence of [Fe(CO)~5~] gave **2** and **17** (__Scheme 4__). St