๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Structure-reactivity relationships in the chemical hydrolysis of prodrug esters of nicotinic acid

โœ Scribed by Gia Nghi Wernly-Chung, ; Mayer, Joachim M.; Anna, Tsantili-Kakoulidou; Testa, Bernard


Book ID
122432405
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
543 KB
Volume
63
Category
Article
ISSN
0378-5173

No coin nor oath required. For personal study only.


๐Ÿ“œ SIMILAR VOLUMES


Chemical stability, enzymatic hydrolysis
โœ Chun Yang; Hongwu Gao; Ashim K. Mitra ๐Ÿ“‚ Article ๐Ÿ“… 2001 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 183 KB ๐Ÿ‘ 1 views

The objective of this work was to improve nasal absorption of relatively impermeable small drug molecules via an amino acid prodrug approach. Acyclovir was selected as a model drug. L-Aspartate beta-ester, L-lysyl, and L-phenylalanyl esters of acyclovir were synthesized to investigate their effectiv