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Structure of the T cell receptor in a TiαVβ2,αVβ8-positive T cell line

✍ Scribed by Xiaohong Hou; Jes Dietrich; Jan Kuhlmann; Anne-Marie K. Wegener; Carsten Geisler


Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
648 KB
Volume
24
Category
Article
ISSN
0014-2980

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Our analysis of TCR V gene usage in mice transgenic for the Vb8.2 gene has demonstrated that T cells isolated from the spinal cord of these transgenic mice during active experimental autoimmune encephalomyelitis were significantly biased for Va2 expression. This Va2 bias was noted in T cells derived