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Structure of the ribosome-bound cricket paralysis virus IRES RNA

✍ Scribed by Giesebrecht, Jan; Dabrowski, Marylena; Schroeer, Birgit; Mielke, Thorsten; Penczek, Pawel A; Westhof, Eric; Spahn, Christian M T; Schüler, Martin; Connell, Sean R; Lescoute, Aurelie


Book ID
109966593
Publisher
Nature Publishing Group
Year
2006
Tongue
English
Weight
552 KB
Volume
13
Category
Article
ISSN
1545-9993

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## Abstract Many viruses reprogram ribosomes to produce two different proteins from two different reading frames. So‐called −1 frameshifting often involves pairwise alignment of two adjacent tRNAs at a ‘slippery' sequence in the ribosomal A and P sites such that an overlapping codon is shifted upst