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Structure of the neuroleptic drug 4-amino-N-1-[(1-ethyl-2-pyrrolidinyl)methyl]-5-(ethylsulfonyl)-2-methoxybenzamide (amisulpride)

✍ Scribed by De Winter, H. L. ;Verlinde, C. L. ;Blaton, N. M. ;Peeters, O. M. ;De Ranter, C. J.


Book ID
114506680
Publisher
International Union of Crystallography
Year
1990
Tongue
English
Weight
599 KB
Volume
46
Category
Article
ISSN
0108-2701

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✍ Jogeshwar Mukherjee πŸ“‚ Article πŸ“… 1991 πŸ› Elsevier Science βš– 699 KB

Synthesis of a fluorinated benzamide neuroleptic, (S)-N-[(1-ethyl-2- pyrrolidinyl)methyl]-5-(3-fluoropropyl)-2,3- dimethoxybenzamide starting from 3-(3,4-dimethoxyphenyl)-1-propanol in 20-25% overall yield is reported. Radiosynthesis of (S)-N-[(1-ethyl-2-pyrrolidinyl)methyl]- 5-(3[18F]fluoropropyl)-