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Structure of the Mouse Cytochrome P1-450 Genomic Gene

✍ Scribed by Michitoshi NAKAMURA; Masahiko NEGISHI; Mario ALTIERI; Yuan-Tsong CHEN; Toshihiko IKEDA; Robert H. TUKEY; Daniel W. NEBERT

Book ID
115121879
Publisher
John Wiley and Sons
Year
1983
Tongue
English
Weight
871 KB
Volume
134
Category
Article
ISSN
1432-1327

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## Abstract Summary: NADPH‐cytochrome P450 reductase (CPR or POR) is the obligatory electron donor for all microsomal cytochrome P450 (CYP or P450)‐catalyzed monooxygenase reactions. Disruption of the mouse __Cpr__ gene has been reported to cause prenatal developmental defects and embryonic lethali