Identification of complex genomic breakp
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Heidi Gill Super; Pamela L. Strissel; Olatoyosi M. Sobulo; Dennis Burian; Shalin
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Article
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1997
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John Wiley and Sons
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English
⚖ 154 KB
👁 3 views
The MLL gene at chromosome 11, band q23, is involved in translocations with as many as 40 different chromosomal bands. Virtually all breakpoints occur within an 8.3 kb BamHI fragment and result in 5' MLL fused to partner genes in a 5'-3' orientation. The translocation t(9;11)(p22;q23), which results