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Structure of the lactam of guanidinoglutaric acid (N-Amidinoglutamic acid)

✍ Scribed by Samuel Natelson; Fred M. Schell

Book ID
103268275
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
457 KB
Volume
42
Category
Article
ISSN
0026-265X

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πŸ“œ SIMILAR VOLUMES

The lactam of Ξ±-guanidinoglutaric acid (
The lactam of Ξ±-guanidinoglutaric acid (1-amidino-2-pyrrolidone-5-carboxylic acid)
✍ Samuel Natelson πŸ“‚ Article πŸ“… 1986 πŸ› Elsevier Science 🌐 English βš– 535 KB

alpha-Guanidinoglutaric acid (alpha-GGA) has been reported to occur in the cerebral cortex after epileptic seizures. No physical characteristics of alpha-GGA have been given. A practical procedure for the preparation of alpha-GGA is reported here. alpha-GGA forms a lactam in aqueous solution at 80 d

Incorporation of N-amidino-pyroglutamic
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✍ Sergey Burov; Yulia Moskalenko; Marina Dorosh; Zoya Shkarubskaya; Evgeny Panarin πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 221 KB

## Abstract __N__‐terminal modification of peptides by unnatural amino acids significantly affects their enzymatic stability, conformational properties and biological activity. Application of __N__‐amidino‐amino acids, positively charged under physiological conditions, can change peptide conformati