The Advantages of Haplotype Analysis of
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Daniel Peter McLaughlin; Anita Sharma; Ann McGinley; Gurdip Singh Samra
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Article
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2001
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Elsevier Science
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English
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Polymorphisms in the regulatory region of the human apolipoprotein E gene (gene, APOE; protein, apoE) have been implicated in Alzheimer's disease. Here we describe in detail the advantages of a simple method for haplotype analysis of this region (at -491 and -427 bases relative to the transcription