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Structure of the Fc fragment of human IgE bound to its high-affinity receptor FcεRIα

✍ Scribed by Jardetzky, Theodore S.; Garman, Scott C.; Wurzburg, Beth A.; Tarchevskaya, Svetlana S.; Kinet, Jean-Pierre


Book ID
109770270
Publisher
Nature Publishing Group
Year
2000
Tongue
English
Weight
431 KB
Volume
406
Category
Article
ISSN
0028-0836

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## Abstract We have recently reported on a class of IgE‐binding peptides designed based on the crystallographic structure of the high affinity FcεRI. Peptides contain receptor key residues located within the two distinct binding sites for IgE and selectively bind IgE with an affinity ranging betwee