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Structure of the double-stranded RNA-binding domain of the protein kinase PKR reveals the molecular basis of its dsRNA-mediated activation

โœ Scribed by Nanduri, Sambasivarao; Carpick, Bruce W.; Yang, Yanwu; Williams, Bryan R.G.; Qin, Jun

Book ID
111745649
Publisher
Nature Publishing Group
Year
1998
Tongue
English
Weight
401 KB
Volume
17
Category
Article
ISSN
0261-4189

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โœ Ryter, J. M. ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› Nature Publishing Group ๐ŸŒ English โš– 644 KB

Protein interactions with double-stranded RNA (dsRNA) are critical for many cell processes; however, in contrast to protein-dsDNA interactions, surprisingly little is known about the molecular basis of protein-dsRNA interactions. A large and diverse class of proteins that bind dsRNA do so by utilizi