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Structure of the Acid-sensing ion channel 1 in complex with the gating modifier Psalmotoxin 1

✍ Scribed by Dawson, Roger J.P.; Benz, Jörg; Stohler, Peter; Tetaz, Tim; Joseph, Catherine; Huber, Sylwia; Schmid, Georg; Hügin, Daniela; Pflimlin, Pascal; Trube, Gerd; Rudolph, Markus G.; Hennig, Michael; Ruf, Armin


Book ID
118125589
Publisher
Nature Publishing Group
Year
2012
Tongue
English
Weight
620 KB
Volume
3
Category
Article
ISSN
2041-1723

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## Abstract The epithelial Na^+^ channel/degenerin (ENaC/DEG) protein family includes a diverse group of ion channels, including nonvoltage‐gated Na^+^ channels of epithelia and neurons, and the acid‐sensing ion channel 1 (ASIC1). In mammalian epithelia, ENaC helps regulate Na^+^ and associated wat