Binding of synthetic peptides by a human
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Allen B. Edmundson; Gordon Tribbick; Sonja Plompen; H. Mario Geysen; Elizabeth Y
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Article
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2001
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John Wiley and Sons
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English
⚖ 294 KB
## Abstract Using X‐ray crystallography, a human monoclonal IgM cryoglobulin (Mez) was found to have an unusual combining site topography. Analysis of the unliganded Fv at 2.6 Å resolution revealed that the HCDR3 had partitioned the active site into two compartments [Ramsland PA __et al.__ 2000. __