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Structure of Human Urokinase Plasminogen Activator in Complex with Its Receptor

✍ Scribed by Huai, Q.

Book ID
111868143
Publisher
American Association for the Advancement of Science
Year
2006
Tongue
English
Weight
433 KB
Volume
311
Category
Article
ISSN
0036-8075

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## Abstract Urokinase plasminogen activator (uPA) and its receptor (uPAR) are overexpressed in various neoplasms, and play a key role in tumor progression and metastasis. In this study, we examined uPA and uPAR expression in a variety of human breast cancer cell lines and found that lines with elev