Structure of human serum cholinesterase

✍ Scribed by Oksana Lockridge

• Book ID: 101711387
• Publisher: John Wiley and Sons
• Year: 1988
• Tongue: English
• Weight: 468 KB
• Volume: 9
• Category: Article
• ISSN: 0265-9247
• DOI: 10.1002/bies.950090406

✦ Synopsis

Human cholinesterase has recently been sequenced and cloned. It is a glycoprotein of 4 identical subunits, each subunit containing 9 carbohydrate chains and 3.5 disuljide bonds. Protein folding is likely to be very similar in human cholinesterase and Torpedo acetylcholinesterase. The cholinesterases have no significant sequence homology with the serine proteases and seem to belong to a separate serine esterase family.