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Structure of human guanylate-binding protein 1 representing a unique class of GTP-binding proteins

✍ Scribed by Prakash, Balaji; Praefcke, Gerrit J. K.; Renault, Louis; Wittinghofer, Alfred; Herrmann, Christian


Book ID
109767502
Publisher
Nature Publishing Group
Year
2000
Tongue
English
Weight
528 KB
Volume
403
Category
Article
ISSN
0028-0836

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## Abstract Rap1 is a small GTP‐binding protein (SMG) that exists in two 95% homologous isoforms, rap1A and rap1B. The functions of the rap1 proteins are not well understood. In this report we examined expression and function of rap1 in primary (HOKs) and immortalized (IHOKs) human oral keratinocyt