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Structure of Hepatitis B Surface Antigen from Subviral Tubes Determined by Electron Cryomicroscopy

โœ Scribed by Judith M. Short; Shaoxia Chen; Alan M. Roseman; P. Jonathan G. Butler; R. Anthony Crowther


Book ID
116664122
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
456 KB
Volume
390
Category
Article
ISSN
0022-2836

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Electron microscopic studies of the morphology of hepatitis B surface antigen (HBsAg) produced by PLC/PRF/5 cells in vitro were carried out. Aggregates of 20-nm spherical particles in 3-day culture supernatants were observed by immune electron microscopy (IEM). Aggregates of tubular structures were