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Structure of hemiaminal intermediate of the reaction of diethylamine with cyclobutanone

โœ Scribed by Dmitry S. Yufit; Judith A.K. Howard


Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
458 KB
Volume
984
Category
Article
ISSN
0022-2860

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Cyclobutanones for the stereoselective s
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Beckmann fragmentation of the oximes 5 and 6 respectiveZy, which were derived from -the cyclobutanones Sand 5, furnished the bifunctional five carbon units 7 and g with ea. 98% -and 91% stereoselectivity. We were interested for some time in the possible control of vicinal stereochemistry in open cha

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## Abstract The reactions of 3โ€chloroโ€3โ€(chlorosulfanyl)โ€2,2,4,4โ€tetramethylcyclobutanโ€1โ€one (**2**) with N, O, S, and P nucleophiles occur by substitution of Cl at the Sโ€atom. Whereas, in the cases of secondary amines, alkanols, phenols, thiols, thiophenols, and diโ€ and trialkyl phosphates, the in