Structure of hemiaminal intermediate of the reaction of diethylamine with cyclobutanone
โ Scribed by Dmitry S. Yufit; Judith A.K. Howard
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 458 KB
- Volume
- 984
- Category
- Article
- ISSN
- 0022-2860
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Beckmann fragmentation of the oximes 5 and 6 respectiveZy, which were derived from -the cyclobutanones Sand 5, furnished the bifunctional five carbon units 7 and g with ea. 98% -and 91% stereoselectivity. We were interested for some time in the possible control of vicinal stereochemistry in open cha
## Abstract The reactions of 3โchloroโ3โ(chlorosulfanyl)โ2,2,4,4โtetramethylcyclobutanโ1โone (**2**) with N, O, S, and P nucleophiles occur by substitution of Cl at the Sโatom. Whereas, in the cases of secondary amines, alkanols, phenols, thiols, thiophenols, and diโ and trialkyl phosphates, the in