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Structure of a Hydroxymycolic Acid Potentially Involved in the Synthesis of Oxygenated Mycolic Acids of the Mycobacterium Tuberculosis Complex

✍ Scribed by Annaïk Quémard; Marie-Antoinette Lanéelle; Hédia Marrakchi; Danielle Prome; Eugenie Dubnau; Mamadou Daffé


Book ID
115133591
Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
661 KB
Volume
250
Category
Article
ISSN
1432-1327

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Trans mycolic acid content is directly related to cell wall fluidity and permeability in mycobacteria. Carbon-13 NMR spectroscopy of mycolic acids isolated from Mycobacterium tuberculosis (MTB) and Mycobacterium smegmatis (MSM) fed 13 C-labeled precursor molecules was used to probe the biosynthetic