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Structure of a Heterophilic Adhesion Complex between the Human CD2 and CD58 (LFA-3) Counterreceptors

✍ Scribed by Jia-huai Wang; Alex Smolyar; Kemin Tan; Jin-huan Liu; Mikyung Kim; Zhen-yu J Sun; Gerhard Wagner; Ellis L Reinherz


Book ID
117267709
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
517 KB
Volume
97
Category
Article
ISSN
0092-8674

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## Abstract Serum‐free culture of human monocytes in the presence of monoclonal antibodies to the LFA‐1 α chain (CD11a), CR3 α chain (CD11b) or β chain (CD18) bound to Sepharose induced the dose‐dependent production of cell‐associated interleukin (IL) 1 activity and of IL 1α and IL 1β antigens, but