Structure of 7-chloro-5-(2,6-dichlorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one
โ Scribed by Kemmish, H. J. ;Hamor, T. A.
- Book ID
- 114504075
- Publisher
- International Union of Crystallography
- Year
- 1988
- Tongue
- English
- Weight
- 349 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0108-2701
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๐ SIMILAR VOLUMES
## Abstract Two benzodiazepines, Diazepam and Flunitrazepam, labeled with carbonโ14 in position 5 of the diazepine ring have been synthesized. Use of a condensation between iminochlorides and ^14^Cโbenzonitriles, followed by exhaustive methylation of the resulting quinazolines and hydrolyses is des
## Abstract 7โChloroโ5โ(2โchlorophenyl)โ1,3โdihydroโ2Hโ1,4โbenzodiazepinโ2โone labeled with carbonโ14 in carbon 5 of the diazepine ring has been synthesized. The compound was prepared in a multistep synthesis from barium carbonateโ^14^C in an overall yield of 23%.