Synthesis of 5β-alkylthebaines, 5β-alkyl
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R. H. Woudenberg; B. E. Oosterhoff; T. S. Lie; L. Maat
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Article
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2010
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Elsevier Science
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English
⚖ 785 KB
## Abstract 5β‐Ethylthebaine (3), together with 5β‐butylthebaine (4), was obtained from thebaine (1) after reaction with butyllithium and ethyl iodide. With butyllithium and diethyl sulfate, thebaine yielded 5β‐ethylthebaine (3), 5β, 10α‐diethylthebaine (5), and 5β, 10α, 10β‐triethylthebaine (6). T