Structure of 3,6-bis(dimethylamino)-2,5-diisopropylthieno[3,2-b]thiophene
✍ Scribed by Heinemann, F. ;Hartung, H. ;Hansen, J. ;Maschmeier, C. P. ;Matschiner, H.
- Book ID
- 114509727
- Publisher
- International Union of Crystallography
- Year
- 1992
- Tongue
- English
- Weight
- 316 KB
- Volume
- 48
- Category
- Article
- ISSN
- 0108-2701
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📜 SIMILAR VOLUMES
On heating in sulpholane 4,6-dihydrothieno[3,4-blthiophene 5,5-dioxides give 2,3dihydro-2,3-bis(methylene)thiophenes which can be intercepted in Diels-Alder reactions. Sulphur dioxide is a very efficient trap for these thiophene xylylenes giving the cyclic sulphones by cheletropic addition.
A series of the title compounds were prepared for evaluation as inhibitors of carbonic anhydrase II. Oxidation of 5-substituted thieno[2,3-b]thiophene-2-sulfonamides provided the first examples of thiophene[2,3-b]thiophene-2-sulfonamide 6,6-dioxides. These cyclic vinyl sulfones readily underwent add