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Structure of 2-[(4-cyanophenyl)methylene]-1,3-dithiole-4,5-dicarboxylic acid, dimethyl ester

โœ Scribed by van Veggel, F. C. J. M. ;Harkema, S.


Book ID
114508786
Publisher
International Union of Crystallography
Year
1992
Tongue
English
Weight
311 KB
Volume
48
Category
Article
ISSN
0108-2701

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โœ Robert B. Palmer; Niels H. Andersen ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 242 KB

We report the synthesis and X-ray crystal structure of 1,4-dihydro-2,6-dimethyl-4-(2'isopropylphenyl)-3,5-pyridine-dicarboxylic acid dimethyl ester (4), an analogue of the 1,4dihydropyridine calcium channel antagonist, nifedipine. Solution state NOE data indicate the presence of both rotameric forms