Serpins are members of a family of structurally related protein inhibitors of serine proteinases, with molecular masses between 40 and 100kDa. In contrast to other, simpler, proteinase inhibitors, they may interact with proteinases as inhibitors, as substrates, or as both. They undergo conformationa
Structure-Function Relationship in the Serotransferrin: The Role of the pH on the Conformational Change and the Metal Ions Release
โ Scribed by A.C. Castellano; M. Barteri; M. Castagnola; A. Bianconi; E. Borghi; S. Dellalonga
- Book ID
- 115574129
- Publisher
- Elsevier Science
- Year
- 1994
- Tongue
- English
- Weight
- 308 KB
- Volume
- 198
- Category
- Article
- ISSN
- 0006-291X
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Kinetic parameters for the metal ion activation of calcineurin at 30ยฐC were found to be correlated to the formation constants (log K 1 ) of the activating metal ions (Mn 2+ , Co 2+ , Ni 2+ , Zn 2+ , and Mg 2+ ) with the substrate para-nitrophenyl phosphate (pNPP). Metal ion activation measured by k