Structure, function and regulation of the plant vacuolar H+-translocating ATPase

✍ Scribed by Rafael Ratajczak

• Book ID: 117047564
• Publisher: Elsevier Science
• Year: 2000
• Tongue: English
• Weight: 674 KB
• Volume: 1465
• Category: Article
• ISSN: 0005-2736
• DOI: 10.1016/s0005-2736(00)00129-2

✦ Synopsis

The plant V-ATPase is a primary-active proton pump present at various components of the endomembrane system. It is assembled by different protein subunits which are located in two major domains, the membrane-integral V o -domain and the membrane peripheral V 1 -domain. At the plant vacuole the V-ATPase is responsible for energization of transport of ions and metabolites, and thus the V-ATPase is important as a `house-keeping' and as a stress response enzyme. It has been shown that transcript and protein amount of the V-ATPase are regulated depending on metabolic conditions indicating that the expression of V-ATPase subunit is highly regulated. Moreover, there is increasing evidence that modulation of the holoenzyme structure might influence V-ATPase activity.