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Structure elucidation of the new citharoxazole from the Mediterranean deep-sea sponge Latrunculia (Biannulata) citharistae

✍ Scribed by Grégory Genta-Jouve; Nellie Francezon; Alexandre Puissant; Patrick Auberger; Jean Vacelet; Thierry Pérez; Angelo Fontana; Ali Al Mourabit; Olivier P. Thomas


Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
160 KB
Volume
49
Category
Article
ISSN
0749-1581

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✦ Synopsis


Abstract

Citharoxazole (1), a new batzelline derivative featuring a benzoxazole moiety, was isolated from the Mediterranean deep‐sea sponge Latrunculia (Biannulata) citharistae Vacelet, 1969, together with the known batzelline C (2). This is the first chemical study of a Mediterranean Latrunculia species and the benzoxazole moiety is unprecedented for this family of marine natural products. The structure was mainly elucidated by the interpretation of NMR spectra and especially HMBC correlations. Copyright © 2011 John Wiley & Sons, Ltd.