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Structure elucidation and NMR assignments for three anthraquinone derivatives from the marine fungus Fusarium sp. (No. ZH-210)

✍ Scribed by Yiguang Chen; Xiaoling Cai; Jiahui Pan; Junping Gao; Jing Li; Jie Yuan; Liwu Fu; Zhigang She; Yongcheng Lin

Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
92 KB
Volume
47
Category
Article
ISSN
0749-1581

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✦ Synopsis

Abstract

The structure elucidations and complete ^1^H and ^13^C NMR assignments are reported for three new anthraquinone derivatives: Fusaquinon A (1), B (2), and C (3) isolated from the fermentation medium of the marine fungus Fusarium sp. (No. ZH‐210). HREIMS, Fourier transform infrared absorption spectrometry (FT‐IR), NMR experiments including gCOSY, gHMQC, gHMBC, and NOESY were used for the determination of the structures and NMR spectral assignments. Preliminary pharmacological test showed that they exhibited low cytotoxic activity towards KB, KBv200, and MCF‐7 cell lines. Copyright © 2009 John Wiley & Sons, Ltd.

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