Structure elucidation and complete NMR spectral assignments of three new lanostanoid triterpenes with unprecedented Δ16, 17 double bond from Ganoderma lucidum
✍ Scribed by Shu-Hong Guan; Min Yang; Xiao-Ming Wang; Jia-Meng Xia; Zhi-Ming Zhang; Xuan Liu; De-An Guo
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 104 KB
- Volume
- 45
- Category
- Article
- ISSN
- 0749-1581
- DOI
- 10.1002/mrc.2046
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✦ Synopsis
Abstract
Three new lanostanoid triterpenes named 3β,7β‐di‐ hydroxy‐11,15,23‐trioxo‐lanost‐8,16‐dien‐26‐oic acid (1), 3β,7β‐dihydroxy‐11,15,23‐trioxo‐lanost‐8,16‐dien‐26‐oic acid methyl ester (2), and 12β‐acetoxy‐3β,7β‐dihydroxy‐11,15,23‐trioxo‐lanost‐8,16‐dien‐26‐oic acid (3) were isolated from the fruit bodies of Ganoderma lucidum. They all show a Δ^16, 17^ double bond unprecedented in such types of lanostanoid triterpenes possessing the side chain at C‐17. The complete NMR assignments for these compounds were carried out using ^1^H, ^13^C, DEPT, COSY, HSQC, HMBC, and ROESY NMR experiments. Copyright © 2007 John Wiley & Sons, Ltd.