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Structure, dynamics and binding characteristics of the second PDZ domain of PTP-BL

✍ Scribed by Tine Walma; Christian A.E.M Spronk; Marco Tessari; Jan Aelen; Jan Schepens; Wiljan Hendriks; Geerten W Vuister


Book ID
115631689
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
467 KB
Volume
316
Category
Article
ISSN
0022-2836

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**Abstract** **Background:** In the mouse submembranous protein tyrosine phosphatase PTP‐BL five PDZ domains are present in between the N‐terminal FERM domain, which directs the protein to the cell cortex, and the C‐terminal catalytic phosphatase domain. To understand more on the physical role of PT