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Structure determination of selaginellins G and H from Selaginella pulvinata by NMR spectroscopy

✍ Scribed by Yuan Cao; Ji-Jun Chen; Ning-Hua Tan; Yong-Ping Wu; Jie Yang; Qiang Wang

Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
111 KB
Volume
48
Category
Article
ISSN
0749-1581

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✦ Synopsis

Abstract

Selaginellins G (1) and H (2), two new selaginellin derivatives, were isolated from the whole plant of Selaginella pulvinata. Their structures were elucidated, and complete assignments of the ^1^H and ^13^C NMR spectroscopic data were achieved by 1D and 2D NMR experiments (HSQC, HMBC, COSY and ROESY). Compound 1 displayed good antifungal activity against Candida albicans with an IC~50~ value of 5.3 µg/ml. Copyright © 2010 John Wiley & Sons, Ltd.

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