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Structure determination of germacrane-type sesquiterpene alcohols from an endophyte Streptomyces griseus subsp.

✍ Scribed by Shuhong Guan; Susanne Grabley; Ingrid Groth; Wenhan Lin; Arnulf Christner; Dean Guo; Isabel Sattler


Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
94 KB
Volume
43
Category
Article
ISSN
0749-1581

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✦ Synopsis


Three germacrane-type sesquiterpene alcohols were isolated from an endophyte of mangrove plant Kandelia candel. Their structures were characterized as 1(10)E,5E-germacradiene-11-ol (1), 1(10)E,5Egermacradiene-3,11-diol (2), 1(10)E,5E-germacradiene-2,11-diol (3) based on the extensive NMR studies. Among them, 2 and 3 are identified as new compounds.


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✍ Xiao-chi Ma; Jian Zheng; Li-jun Wu; De-an Guo 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 108 KB

## Abstract Five germacrane‐type sesquiterpene alcohols obtained from curdione (1) by microbial biotransformation were isolated. Their structures were characterized as (2__R__)‐2β‐hydroxycurdione (2), 1α, 10β‐epoxy‐11‐hydroxycurdione (3), (2__S__)‐2α, 11‐dihydroxycurdione (4), 11,15‐dihydroxycurdio