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Structure determination of chamaedryosides A—C, three novel nor-neo-clerodane glucosides from Teucrium chamaedrys, by NMR spectroscopy

✍ Scribed by Antonio Fiorentino; Brigida D'Abrosca; Andreina Ricci; Severina Pacifico; Simona Piccolella; Pietro Monaco


Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
149 KB
Volume
47
Category
Article
ISSN
0749-1581

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✦ Synopsis


Abstract

Three new nor‐neo‐clerodane diterpenes, named chamaedryoside A (1), B (2) and C (3), have been isolated from the organic extracts of Teucrium chamaedrys (L.) and their structural characterization has been accomplished by ^1^H and ^13^C‐NMR spectra, and DEPT, by COSY, TOCSY, HSQC, HSQC‐TOSCY and HMBC experiments, as well as by ESI‐MS/MS techniques. The stereostructures have been elucidated by NOESY and computational calculations. Copyright © 2009 John Wiley & Sons, Ltd.


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