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Structure, Biological Activity and Synthesis of Polyamine Analogues and Conjugates

✍ Scribed by George Karigiannis; Dionissios Papaioannou

Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
809 KB
Volume
2000
Category
Article
ISSN
1434-193X

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✦ Synopsis

The structure and the biological significance of naturally occurring and synthetic polyamine analogues and conjugates are presented and the available methodologies for their synthesis are described. These methodologies involve either the selective functionalization of the amino functions, using suitable protecting groups or acylating agents, or fragment synthesis protocols. The latter employ suitable amino compon-

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