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Structure Based Prediction of Binding Affinity of Human Immunodeficiency Virus-1 Protease Inhibitors

โœ Scribed by Kulkarni, S.S.; Kulkarni, V.M.


Book ID
126201404
Publisher
American Chemical Society
Year
1999
Tongue
English
Weight
168 KB
Volume
39
Category
Article
ISSN
0095-2338

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The design and synthesis of compounds targeted against human immunodeficiency virus 1 (HIV-1) protease have resulted in effective antiviral therapies. However, the rapid replication of the virus and the inherent mutability of the viral genome result in the outgrowth of resistant strains in the major