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Structure-based ligand design for flexible proteins: Application of new F-DycoBlock

✍ Scribed by Jiang Zhu; Hao Fan; Haiyan Liu; Yunyu Shi

Book ID
110331216
Publisher
Springer Netherlands
Year
2001
Tongue
English
Weight
450 KB
Volume
15
Category
Article
ISSN
0920-654X

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## Abstract P‐Glycoprotein (P‐gp), a transmembrane, ATP‐dependent drug efflux transporter, has attracted considerable interest both with respect to its role in tumour cell multidrug resistance and in absorption‐distribution and elimination of drugs. Although known since more than 30 years, the unde