𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Structure-based drug design to the discovery of new 2-aminothiazole CDK2 inhibitors

✍ Scribed by Anna Vulpetti; Elena Casale; Fulvia Roletto; Raffaella Amici; Manuela Villa; Paolo Pevarello


Book ID
108181065
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
453 KB
Volume
24
Category
Article
ISSN
1093-3263

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


ChemInform Abstract: Discovery of Potent
✍ Brian N. Cook; et al. et al. πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons βš– 18 KB πŸ‘ 1 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a β€œFull Text” option. The original article is trackable v

Structure-based drug design of nonpeptid
✍ Vincent J. Kalish; John H. Tatlock; Jay F. Davies II; Stephen W. Kaldor; Bruce A πŸ“‚ Article πŸ“… 1995 πŸ› Elsevier Science 🌐 English βš– 290 KB

The cocrystal structures of LY289612 and LY297135 were used as a starting point in the design of nonpeptidic HIV-1 protease inhibitors. This report details the discovery of a series of novel aromatic P2 replacement groups. The 3-hydroxy-2-methyl benzoic acid group, discovered in AG1254, was incorpor