𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Structure-Based Discovery of Small Molecule Inhibitors Targeted to Protein Tyrosine Phosphatase 1B

✍ Scribed by Sarmiento, Mauro; Wu, Li; Keng, Yen-Fang; Song, Li; Luo, Zhaowen; Huang, Ziwei; Wu, Guo-Zhang; Yuan, Adam K.; Zhang, Zhong-Yin


Book ID
111928117
Publisher
American Chemical Society
Year
2000
Tongue
English
Weight
315 KB
Volume
43
Category
Article
ISSN
0022-2623

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Discovery and SAR of novel, potent and s
✍ Zhonghua Pei; Xiaofeng Li; Gang Liu; Cele Abad-Zapatero; Tom Lubben; Tianyuan Zh πŸ“‚ Article πŸ“… 2003 πŸ› Elsevier Science 🌐 English βš– 211 KB

A salicylate second site binder was linked to three classes of phosphotyrosine mimetics to produce potent protein tyrosine phosphatase 1B (PTP1B) inhibitors which exhibit significant selectivity against other phosphatases including the most homologous member, TCPTP.