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Structure-Based Design and Synthesis of Dipeptide Analogues as New Inhibitors of Leucine Aminopeptidase

✍ Scribed by Grembecka, Jolanta; Mucha, Artur; Cierpicki, Tomasz; Kafarski, Paweł


Book ID
126569551
Publisher
Taylor and Francis Group
Year
2002
Tongue
English
Weight
91 KB
Volume
177
Category
Article
ISSN
1042-6507

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## Abstract This work deals with the design and synthesis of α‐glucosidase inhibitors. In order to perform this task, a molecular docking study was carried out with the __N__‐terminal catalytic subunit of human maltase glucoamylase, which evidenced a partially empty, hydrophobic part of the docking