Insights into the mechanisms of catalysi
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Lei Jin; Boguslaw Stec; William N. Lipscomb; Evan R. Kantrowitz
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Article
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1999
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John Wiley and Sons
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English
โ 529 KB
A high-resolution structure of Escherichia coli aspartate transcarbamoylase has been determined to 2.1 ร ; resolution in the presence of the bisubstrate analog N-phosphonacetyl-L-aspartate (PALA). The structure was refined to a free R-factor of 23.4% and a working R-factor of 20.3%. The PALA molecule