𝔖 Bobbio Scriptorium
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Structure and regulation of the porcine skeletal α-actin-encoding gene

✍ Scribed by James M. Reecy; Christopher A. Bidwell; Glenn P. Briley; Alan L. Grant


Book ID
117521825
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
584 KB
Volume
180
Category
Article
ISSN
0378-1119

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The ACTA1 gene encodes skeletal muscle a-actin, which is the predominant actin isoform in the sarcomeric thin filaments of adult skeletal muscle, and essential, along with myosin, for muscle contraction. ACTA1 disease-causing mutations were first described in 1999, when a total of 15 mutations were