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Structure and Inter-domain Interactions of Domain II from the Blood-stage Malarial Protein, Apical Membrane Antigen 1

✍ Scribed by Zhi-Ping Feng; David W. Keizer; Rachel A. Stevenson; Shenggen Yao; Jeffrey J. Babon; Vince J. Murphy; Robin F. Anders; Raymond S. Norton


Book ID
116662201
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
678 KB
Volume
350
Category
Article
ISSN
0022-2836

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## Abstract Membrane protein Nramp1 (natural resistance‐associated macrophage protein 1) is a pH‐dependent divalent metal cation transporter that regulates macrophage activation in infectious and autoimmune diseases. A naturally occurring glycine to aspartic acid substitution at position 169 (G169D