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Structure and hydration properties of hydroxypropyl methylcellulose matrices containing naproxen and naproxen sodium

✍ Scribed by Ifat Katzhendler; Karsten Mäder; Michael Friedman


Book ID
108453850
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
247 KB
Volume
200
Category
Article
ISSN
0378-5173

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From a mixture of a methanol solution of ibuprofen (IB) and an aqueous solution of hydroxypropyl methylcellulose (HPMC), clear, uniform sol was obtained at the methanol/water proportion 7/3. When sol was brought to dryness, nanocomposite gel was obtained with amorphous IB particles of 20-50 nm dispe