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Structure and functional significance of the transverse vesical fold

โœ Scribed by N.T. Boaz; A.H. Martin; K. Thompson; C. Ferreira; L. Forest-Nearn

Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
858 KB
Volume
24
Category
Article
ISSN
0897-3806

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Precision scale models of sickle cell hemoglobin molecules indicate that the genetic substitution of valine for glutamic acid at the sixth position in the two p chains allows an intramolecular hydrophobic bond to form. This changes the conformation in such a way as to allow molecular stacking. Resul