Capsaicin, the main ingredient in hot chili peppers, elicits a sensation of burning pain by selectively activating sensory neurons that convey information about noxious stimuli to the central nervous system. The capsaicin receptor, transient receptor potential vanilloid 1 (TRPV1), is predicted to ha
β¦ LIBER β¦
Structure and function of TRPV1
β Scribed by Makoto Tominaga; Tomoko Tominaga
- Publisher
- Springer
- Year
- 2005
- Tongue
- English
- Weight
- 337 KB
- Volume
- 451
- Category
- Article
- ISSN
- 0031-6768
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## Abstract Transient receptor potential vanilloid (TRPV) channels are polymodal detectors of multiple environmental factors, including temperature, pH, and pressure. Inflammatory mediators enhance TRPV function through multiple signaling pathways. The lipoxygenase and epoxygenase products of arach