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Structure and Function of the Oxidation Products of Polyphenols and Identification of Potent Lipoxygenase Inhibitors from Fe-Catalyzed Oxidation of Resveratrol

โœ Scribed by Shingai, Yoshimi; Fujimoto, Aya; Nakamura, Mitsuhiro; Masuda, Toshiya

Book ID
111962875
Publisher
American Chemical Society
Year
2011
Tongue
English
Weight
838 KB
Volume
59
Category
Article
ISSN
0021-8561

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A novel ring-expanded product with enhanced tyrosinase inhibitory activity from classical Fe-catalyzed oxidation of rosmarinic acid, a potent antioxidative Lamiaceae polyphenol
โœ Aya Fujimoto; Yoshimi Shingai; Mitsuhiro Nakamura; Tomomi Maekawa; Yoshiaki Sone ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 234 KB

The iron-ion catalyzed oxidation of the ethanol solution of rosmarinic acid, a potent antioxidant polyphenol of Lamiaceae (Labiatae) plants, afforded a highly tyrosinase-inhibitory active product. The structure of the active product in the oxidation product mixture was determined using extensive NMR