## Abstract The heat‐shock proteins (HSPs) Hsp27 and αB‐crystallin are up‐regulated in Alzheimer's disease (AD), but the extent of this and the consequences are still largely unknown. The HSPs are involved in protein degradation and protection against protein aggregation, and they interact with sev
✦ LIBER ✦
Structure and function of small heat shock/α-crystallin proteins: established concepts and emerging ideas
✍ Scribed by T. H. MacRae
- Publisher
- Springer
- Year
- 2000
- Tongue
- English
- Weight
- 924 KB
- Volume
- 57
- Category
- Article
- ISSN
- 1420-682X
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## Abstract The recently described human HSP22 belongs to the superfamily of small heat‐shock proteins containing a conservative α‐crystallin domain. HSP22 seems to be involved in regulation of cell proliferation, cardiac hypertrophy, apoptosis, and carcinogenesis, and expression of point mutants o