Structure and Function of Cholesteryl Ester Transfer Protein in the Tree Shrew
β Scribed by Huirong Liu; Gang Wu; Bing Zhou; Baosheng Chen
- Book ID
- 107488312
- Publisher
- Springer-Verlag
- Year
- 2011
- Tongue
- English
- Weight
- 446 KB
- Volume
- 46
- Category
- Article
- ISSN
- 0024-4201
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Described herein are the chemical syntheses of 3 beta-hydroxy-5 alpha-cholest-8(14)-en-15-one and 3 beta-hydroxy-5 alpha-cholest-8(14),16-dien-15-one from diosgenin and the examinations of their ability to inhibit the cholesteryl ester transfer protein (CETP). Clemmensen reduction of diosgenin gave